Border Collie Collie Eye Anomaly pedigree — autosomal recessive
This Border Collie pedigree chart illustrates Collie Eye Anomaly as an autosomal recessive condition. Two carrier parents produce an affected female proband. The proband later mates with a carrier male, which makes both an affected and a carrier puppy possible in generation III. Each affected dog in the example has two parents capable of passing on the disease allele.
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Scenario
A Border Collie breeder is reviewing a family affected by Collie Eye Anomaly, an autosomal recessive developmental eye condition.
Key decisions
- The two generation-I parents are carriers, allowing an affected daughter.
- The female proband is affected and therefore has two disease alleles.
- Her carrier mate provides the second disease allele needed for the affected puppy.
- The unaffected generation-II sibling remains genetically unclassified.
When to reuse this
Use this case to explain a recessive dog-breeding pedigree alongside DNA testing and veterinary ophthalmic assessment. It is not a substitute for clinical or breeding advice.
Frequently asked questions
Is Collie Eye Anomaly recessive?
Why can the affected proband have an affected puppy?
Does an unaffected dog have clear status?
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