Type 2 diabetes feedback loops
This causal loop diagram summarises a feedback pattern often used to explain progression in type 2 diabetes. Insulin resistance can raise blood glucose, which raises the demand placed on beta cells. Sustained stress can reduce insulin secretion over time, allowing glucose to rise further. Glucotoxicity is included as another route by which elevated glucose may worsen beta-cell stress. The signed arrows help learners check whether each link moves in the same or opposite direction. This is a simplified teaching model: real disease progression also involves genetics, body composition, medicines and many other factors. It should not be used to diagnose a person or to choose treatment. Add variables only when their causal direction can be explained clearly.
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Scenario
Type 2 diabetes teaching
Key decisions
- Variables: Use measurable physiological states.
- Polarity: Mark secretion as lowering glucose.
- Delay: Show the gradual beta-cell response.
- Loop: Name the glucose-stress feedback.
When to reuse this
Use as a teaching overview, not for individual diagnosis or treatment.
Frequently asked questions
Why is this a reinforcing loop?
Why is there a delay?
Is this a treatment plan?
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