“A BRCA1 hereditary cancer pedigree: an unaffected man and a deceased affected woman have an affected daughter, an unaffected son and a carrier daughter; the affected daughter has an affected daughter who is the proband, an unaffected son and a presymptomatic daughter; the carrier daughter has a carrier daughter and an unaffected son.”
Die dahinterstehenden Entscheidungen verstehen.
Cancer appears in successive generations.
The affected granddaughter is the proband.
Carrier and presymptomatic relatives are distinguished.
Use this pedigree to organize a hereditary cancer history before a genetics referral.
Häufige Fragen
What is a hereditary cancer pedigree?
It is a family diagram that records relationships, cancer history and, where known, genetic test status.
What does presymptomatic mean?
It identifies a person with a relevant genetic status who has not developed the recorded condition.
Does this chart diagnose BRCA1?
No. A pedigree supports risk assessment but a diagnosis requires appropriate clinical evaluation and testing.