The scenario
A researcher processes single-cell RNA-seq data from pancreatic islets to identify a gene signature specific to beta cells in type 2 diabetes.
What is in this drawing
Read the decisions behind it.
01
Quality control filtering thresholds
02
Beta cell annotation approach
03
Validation strategy for candidate signature
When building a reproducible workflow from scRNA-seq data to derive a cell-type-specific disease gene signature.
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