The scenario
A reproducible pipeline is needed to derive an immune-related gene signature from DLBCL transcriptomic data, from expression matrix to validated nomogram.
What is in this drawing
Read the decisions behind it.
01
Use LASSO Cox regression to select prognostic genes
02
Validate with external cohort
03
Intersect DEGs with immune gene list
When building prognostic gene signatures from RNA-seq or microarray data for cancer subtypes.
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